Asian American immigrant parents supporting children with autism spectrum disorders (ASD) has been understudied. The purpose of this qualitative study was to probe the perceptions of Mandarin-speaking immigrant mothers and fathers raising children with ASD in the United States. Ten participating parents were first-generation native Mandarin-speaking immigrants born in Taiwan, Hong Kong or Mainland China. Open-ended interviews were conducted to collect data. The interviews were transcribed and translated verbatim and analyzed using content analysis. Four main themes by gender comparison were derived from the self-report data: cognitive responses of ASD diagnosis, perceived role, coping strategies and future expectations. Implications for diversity awareness in professional practice and supports to meet the needs of Mothers and Fathers in promoting inclusion were discussed.