Tetrathiomolybdate alleviates osteoporosis by activating the PI3K/Akt signaling axis
1 School of Sport Medicine and Rehabilitation, Beijing Sport University, 100084 Beijing, China
2 Institute of Integrated Bioinfomedicine and Translational Science (IBTS), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
3 Department of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, 430065 Wuhan, Hubei, China
4 School of Medicine, Xiamen University, 361100 Xiamen, Fujian, China
5 Department of Spinal Surgery, The Second Affiliated Hospital of Guangzhou Medical University, 510260 Guangzhou, Guangdong, China
6 Department of Rehabilitation Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, 361003 Xiamen, Fujian, China
§ These authors contributed equally
Graphical Abstract
Keywords
- Tetrathiomolybdate
- osteoporosis
- bone formation
- PI3K/Akt signaling
- ovariectomy
- cuproptosis
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